Understanding allergy immunotherapy: how it works

Understanding Allergy Immunotherapy: How It Works

by Men's Reporter Team

Understanding Allergy Immunotherapy: An Overview

Allergy immunotherapy provides a long-term approach for managing chronic allergies. By gradually exposing the immune system to small quantities of allergens—substances that trigger allergic reactions—it aims to decrease sensitivity over time. This treatment not only alleviates symptoms but can also lead to fewer severe allergic responses as patients build tolerance to those allergens.

Types of Allergy Immunotherapy

1. Allergy Shots

Allergy shots, or subcutaneous immunotherapy (SCIT), represent one of the most prevalent forms of immunotherapy available. They address allergies impacting the eyes, nose, ears, and lungs, effectively targeting a wide range of allergens, including pollen, dust mites, pet dander, and more.

This treatment is typically conducted in two phases:

  • Build-Up Phase: Lasting anywhere from three to six months, this phase involves receiving allergy shots one to two times per week, with doses gradually increasing.
  • Maintenance Phase: Following the build-up, patients transition to monthly shots for three to five years, providing sustained relief from allergies.

It’s important to note that it may take up to one year in the maintenance phase before patients notice a marked improvement in their symptoms.

2. Allergy Tablets

Also known as sublingual immunotherapy (SLIT), allergy tablets dissolve under the tongue and serve as a newer alternative to injections. This method allows patients to develop tolerance by exposing them to small amounts of allergens.

While allergy tablets are approved for a limited number of allergens compared to shots, they have shown effectiveness in treating specific allergies such as grass and ragweed pollen. Patients typically start taking these tablets weeks or months before peak allergy seasons, and many notice symptom improvements around three months after beginning treatment.

Allergy Drops

Similar to tablets, allergy drops are another method but are not FDA-approved for immunotherapy use. Some healthcare providers may prescribe them off-label, which entails using a drug in a manner not specified in the FDA’s approval.

Effectiveness of Allergy Immunotherapy

Research indicates that allergy immunotherapy is effective, although results can vary widely among individuals. While some patients experience significant and lasting reductions in their allergy symptoms, others may see a resurgence if treatment is halted. Overall, immunotherapy can:

  • Prevent the development of new allergies
  • Decrease existing allergy symptoms
  • Mitigate the progression of allergies into related conditions, such as asthma

For many patients, adhering to the prescribed treatment regimen can lead to substantial improvements in quality of life. However, it’s crucial for those who do not experience symptom relief after a year of treatment to consult their healthcare provider regarding the continuation of therapy.

Allergies and Related Health Issues

Individuals with allergies may also experience other health issues such as asthma or conjunctivitis. Allergy shots can help mitigate some symptoms associated with these conditions, enhancing overall well-being.

Potential Side Effects

As with any medical treatment, allergy immunotherapy carries potential side effects. Common reactions may include mild symptoms such as sneezing, hives, and localized redness or swelling at the injection site. Rarely, patients may experience severe allergic reactions, including anaphylaxis. Those receiving allergy shots are monitored for a period post-injection, while those on tablets may be prescribed an EpiPen as a precaution.

Allergy tablets may result in specific side effects occurring in about one in 10,000 doses, including:

  • Irritation in the mouth and throat
  • Gastrointestinal issues such as nausea
  • Allergic reactions affecting the esophagus, leading to swallowing difficulties

Food Allergies and Immunotherapy

While some evidence suggests that immunotherapy may lessen the severity of food allergy reactions, the risks associated—particularly the potential for anaphylaxis—mean it is not generally recommended as an initial treatment option. Individuals with serious food allergies should consult a healthcare provider before considering this therapy, ensuring optimal safety during treatment.

Insurance Coverage for Allergy Immunotherapy

Allergy immunotherapy is often recognized as a cost-effective treatment option and is typically covered by insurance plans. Patients should seek a referral to an allergist, a specialist trained in the management of allergies, to determine personal eligibility and treatment pathways.

Conclusion

Allergy immunotherapy is an established method of desensitizing the immune system to allergens over time, offering potential relief from allergy symptoms. Although this treatment may require a commitment of several years, many find it significantly improves their quality of life. For those struggling with allergies, discussing immunotherapy options with a healthcare provider or allergist could be beneficial.

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