June 8, 2025 — The weight-loss medication Ozempic, known for its efficacy in managing type 2 diabetes and aiding weight reduction, has recently been associated with an unexpected side effect: some male users report a perceived increase in genital size. This phenomenon, colloquially termed “Ozempic penis,” has sparked discussions across online forums and prompted medical professionals to explore potential explanations.
Anecdotal Reports and Observations
Numerous male users of Ozempic and similar GLP-1 receptor agonists have shared personal accounts on platforms like Reddit, noting noticeable changes in their genital appearance following significant weight loss. One user remarked, “I recently measured myself down there and noticed I gained about one inch,” while another claimed a 1.5-inch increase after several months on Tirzepatide, a medication akin to Ozempic .
These self-reported experiences have led to widespread speculation about the underlying causes, with many attributing the changes to factors beyond mere weight loss.
Medical Perspectives on the Phenomenon
Healthcare professionals suggest that the perceived increase in genital size is likely due to the reduction of fat in the pubic area, known as the suprapubic fat pad. Dr. Richard Viney, a consultant urological surgeon at the Queen Elizabeth Hospital in Birmingham, explained, “Men’s penises shorten as they get older due to increasing body fat and increasing prostate size drawing the penis back into the body. It is theoretically possible that new drugs like Ozempic and Wegovy, which are used … and can cause people to lose … ” .
This perspective aligns with the understanding that significant weight loss can lead to a more prominent appearance of existing anatomy, rather than actual tissue growth.
Statistical Data and Broader Trends
Recent data from the UK indicates an increase in average penis size from 5.17 inches in 2022 to 5.63 inches in 2024, marking nearly a 10% rise . While some speculate that the widespread use of weight-loss medications like Ozempic may contribute to this trend, experts caution against drawing direct correlations without comprehensive studies.
Dr. Michael Eisenberg of Stanford University highlighted concerns about rapid changes in reproductive biology, suggesting that environmental factors, such as exposure to hormone-disrupting chemicals, might also play a role in these observed trends .
Cautions and Considerations
While the anecdotal reports are intriguing, medical professionals emphasize the importance of approaching such claims with skepticism. Variations in measurement techniques, temporary physiological changes, and psychological factors can all influence perceptions of genital size. Moreover, the lack of clinical studies specifically investigating the relationship between Ozempic use and changes in male genitalia underscores the need for further research.
Conclusion
The emergence of “Ozempic penis” as a topic of discussion reflects the broader interest in the side effects of weight-loss medications. While user reports suggest a perceived increase in genital size following significant weight loss, medical experts attribute these observations to the reduction of surrounding fat rather than actual tissue growth. As with all medications, individuals are advised to consult healthcare professionals regarding potential side effects and to approach anecdotal claims with critical consideration.